pepsinogen I and II
🔰pepsinogen I and II ⭕The levels of pepsinogen (PG) I and the PGI/II ratio are useful serologic markers for chronic atrophic gastritis. This study evaluated the performance and clinical implications of these markers in patients undergoing endoscopy. This study was carried at the gastrointestinal unit at AL-Yarmouk Teaching Hospital. Blood samples with antral biopsies were obtained from 127 patients who were complaining from gastroduodenal disease. Patients included 64 with chronic gastritis and 30 with gastric carcinoma. A further 33 healthy persons, uninfected with H.pylori were involved as a control group. Every gastric biopsy examined by histology and rapid urease test. In addition, patient's sera were screened for the presence of H.pyloriIgG antibodies, serum level of PGI and PGII. According to the histological data it was demonstrated that the adenocarcinoma patients were more prevalent than other type of gastric cancer. There was a significant p<0.05 increased level of p...
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